Compare 1,000+ train, bus and airline operators on OmioWays to travel from Pisa to Rome
Typical journey times and the lowest fares we found for each way to travel.
Journey times and fares come from Omio's route data, last checked on January 14, 2026. Prices change often and depend on your travel date. We may earn a commission if you book through our links, at no extra cost to you.
Good to know
- By train the journey takes about 2h 23m, with fares from €25; by bus it takes about 4h 14m, with fares from €12.
- Some connections include a change of train or bus. Omio shows the exact timetable and any changes before you book.
Where to stay in Rome
Hotels close to the centre of Rome, from budget to luxury. Prices are typical nightly rates at our last check.
Budget
Mid-range
Upscale
LuxuryHotel prices come from Traveloka, last checked on February 4, 2026, and change with your dates. We may earn a commission if you book through our links, at no extra cost to you.
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About Rome
The Eternal City is an open-air museum where ancient ruins stand alongside Renaissance masterpieces and baroque fountains. Rome offers an intoxicating mix of history, art, and la dolce vita, from the Colosseum to cozy trattorias serving authentic Italian cuisine.
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Return journey
More routes from Pisa
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Frequently asked questions
Quick answers based on current route data.
How long does it take to get from Pisa to Rome?+
The quickest option is usually by train, which takes about 2h 23m.
What is the cheapest way to get from Pisa to Rome?+
The cheapest fares are usually by bus, from around €12. Prices depend on the date and how early you book.
Is there a train from Pisa to Rome?+
Yes. Omio lists train connections from Pisa to Rome, with a typical journey time of about 2h 23m. Some connections may include a change.
Is there a bus from Pisa to Rome?+
Yes. Buses run from Pisa to Rome, with a typical journey time of about 4h 14m and fares from around €12.
