Compare 1,000+ train, bus and airline operators on Omio
Vatican Museums, Sistine Chapel & St Peter’s Basilica Guided Tour
4.542,000 reviews3h
from €69
Check availabilityWays to travel from San Sebastián to Rome
Typical journey times and the lowest fares we found for each way to travel.
Journey times and fares come from Omio's route data, last checked on October 12, 2026. Prices change often and depend on your travel date. We may earn a commission if you book through our links, at no extra cost to you.
Good to know
- Over land, the quickest option is the bus, at about 25h 35m.
- By train the journey takes about 52h 20m, with fares from €433; by bus it takes about 25h 35m, with fares from €83.
- Some connections include a change of train or bus. Omio shows the exact timetable and any changes before you book.
- The flight time covers the flight itself. Allow extra time to reach the airports and pass security, which can make ground transport just as fast on shorter routes.
Top tours and experiences in Rome
The tours and tickets travellers book most, with ratings and reviews from Viator.
Rome: Colosseum, Roman Forum and Palatine Hill Guided Tour
4.625,913 reviews1h 30m
from €59
Check availability
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
4.615,662 reviews3h
from €20
Check availability
All things to do in Rome →
Tours and prices from Viator, a Tripadvisor company. Prices change with your dates. We may earn a commission if you book, at no extra cost to you.
Where to stay in Rome
Hotels close to the centre of Rome, from budget to luxury. Prices are typical nightly rates at our last check.
Budget
Mid-range
Upscale
LuxuryHotel prices come from Traveloka, last checked on February 4, 2026, and change with your dates. We may earn a commission if you book through our links, at no extra cost to you.
Ready to explore Rome?
About Rome
The Eternal City is an open-air museum where ancient ruins stand alongside Renaissance masterpieces and baroque fountains. Rome offers an intoxicating mix of history, art, and la dolce vita, from the Colosseum to cozy trattorias serving authentic Italian cuisine.
Keep exploring
More routes from San Sebastián
San Sebastián to Madrid
Flight · 1h 10m · Train from €22
San Sebastián to Barcelona
Flight · 1h 5m · Bus from €35
San Sebastián to Bilbao
Train · 4h 54m · Train from €18
San Sebastián to Paris
Flight · 4h 15m · Bus from €26
San Sebastián to Valencia
Flight · 3h 20m · Bus from €40
San Sebastián to Pamplona
Train · 2h 5m · Train from €7
San Sebastián to Bordeaux
Bus · 2h 10m · Bus from €13
San Sebastián to Logroño
Bus · 2h 10m · Train from €20
More routes to Rome
Milan to Rome
Flight · 1h 10m · Bus from €6
Florence to Rome
Flight · 50m · Bus from €5
Paris to Rome
Flight · 2h · Flight from €45
Naples to Rome
Flight · 50m · Bus from €5
Venice to Rome
Flight · 1h 10m · Bus from €7
Madrid to Rome
Flight · 2h 20m · Flight from €33
Barcelona to Rome
Flight · 1h 45m · Flight from €22
Munich to Rome
Flight · 1h 35m · Bus from €33
Frequently asked questions
Quick answers based on current route data.
How long does it take to get from San Sebastián to Rome?+
The quickest option is usually by plane, which takes about 4h 20m.
What is the cheapest way to get from San Sebastián to Rome?+
The cheapest fares are usually by flight, from around €62. Prices depend on the date and how early you book.
Is there a train from San Sebastián to Rome?+
Yes. Omio lists train connections from San Sebastián to Rome, with a typical journey time of about 52h 20m. Some connections may include a change.
Is there a bus from San Sebastián to Rome?+
Yes. Buses run from San Sebastián to Rome, with a typical journey time of about 25h 35m and fares from around €83.
