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Can't decide between Cartagena and Panama City? Compare these two amazing destinations to find your perfect match.
Cartagena is a Caribbean jewel of colorful colonial architecture, cobblestone streets, and tropical energy. This walled city enchants with its romantic plazas, vibrant nightlife, nearby islands, and some of the best ceviche in South America.
Known for
Panama City is a striking contrast of old and new — a glittering Manhattan-like skyline beside the UNESCO-listed Casco Viejo historic district. The Panama Canal, tropical rainforests within city limits, and a booming food scene make it Central America's most cosmopolitan capital.
Known for
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See how these destinations stack up in key categories
Cartagena offers Walled City, Castillo San Felipe de Barajas, Getsemaní
Panama City offers Panama Canal (Miraflores Locks), Casco Viejo, BioMuseo
Cartagena is famous for its local dining scene
Panama City is famous for its local dining scene
Cartagena has legendary nightlife
Panama City offers a relaxed evening atmosphere
December to April
December to April
Summer: 32°C, Winter: 30°C
Summer: 32°C, Winter: 30°C
Descubre atracciones menos conocidas en cada ciudad
Convento de la Popa
A 17th-century monastery perched on the highest hill in Cartagena, offering panoramic 360-degree views of the entire city, bay, and coastline.
Mercado de Bazurto
The city's sprawling, chaotic central market where locals buy everything from fresh fish and exotic fruits to household goods and traditional remedies.
Cementerio Amador (Amador Cemetery)
A historic cemetery on a small peninsula near Casco Viejo, with elaborate tombs and stunning views of the bay and skyline.
Mercado de Abastos
The city's massive, bustling wholesale fruit and vegetable market, located near Albrook.
Descubre las mejores zonas para visitar en cada ciudad
Ciudad Amurallada (The Walled City)
The historic heart and soul of Cartagena, enclosed by massive stone walls.
Getsemaní
Once a rough neighborhood, now the city's hip, artistic, and most energetic quarter.
Casco Viejo
The historic heart and soul of the city, a UNESCO World Heritage site of colorful colonial buildings, charming plazas, and cobblestone streets.
Punta Pacifica & Punta Paitilla
The city's modern, affluent waterfront districts, dominated by sleek skyscrapers, luxury condos, and high-end shopping malls like Multiplaza Pacific.
Compara el coste de viajar en cada ciudad
Find tours and experiences in both cities
Salta la cola con tours y atracciones reservadas
Salta la cola con tours y atracciones reservadas
Compare transport options to both destinations
Compara precios de trenes, autobuses y vuelos a Cartagena
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Compara precios de trenes, autobuses y vuelos a Panama City
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Both Cartagena and Panama City are incredible destinations. Cartagena excels in colonial architecture and Caribbean beaches, while Panama City stands out for Panama Canal and Casco Viejo.
Best destination for:
nightlife
Cartagena
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