Compare 1,000+ train, bus and airline operators on OmioWays to travel from Brussels to Madrid
Typical journey times and the lowest fares we found for each way to travel.
Journey times and fares come from Omio's route data, last checked on January 14, 2026. Prices change often and depend on your travel date. We may earn a commission if you book through our links, at no extra cost to you.
Good to know
- Over land, the quickest option is the bus, at about 21h 15m.
- By train the journey takes about 21h 32m, with fares from €409; by bus it takes about 21h 15m, with fares from €51.
- Some connections include a change of train or bus. Omio shows the exact timetable and any changes before you book.
- The flight time covers the flight itself. Allow extra time to reach the airports and pass security, which can make ground transport just as fast on shorter routes.
Where to stay in Madrid
Hotels close to the centre of Madrid, from budget to luxury. Prices are typical nightly rates at our last check.
Budget
Mid-range
Upscale
LuxuryHotel prices come from Traveloka, last checked on February 4, 2026, and change with your dates. We may earn a commission if you book through our links, at no extra cost to you.
Ready to explore Madrid?
About Madrid
Madrid is Spain's elegant capital, where world-class art museums, grand plazas, and vibrant nightlife come together. The Prado and Reina Sofía house masterpieces, while tapas bars and flamenco clubs keep the city alive until dawn.
Keep exploring
Return journey
More routes from Brussels
More routes to Madrid
Frequently asked questions
Quick answers based on current route data.
How long does it take to get from Brussels to Madrid?+
The quickest option is usually by plane, which takes about 2h 20m.
What is the cheapest way to get from Brussels to Madrid?+
The cheapest fares are usually by bus, from around €51. Prices depend on the date and how early you book.
Is there a train from Brussels to Madrid?+
Yes. Omio lists train connections from Brussels to Madrid, with a typical journey time of about 21h 32m. Some connections may include a change.
Is there a bus from Brussels to Madrid?+
Yes. Buses run from Brussels to Madrid, with a typical journey time of about 21h 15m and fares from around €51.
