Compare 1,000+ train, bus and airline operators on OmioWays to travel from Rome to Prague
Typical journey times and the lowest fares we found for each way to travel.
Journey times and fares come from Omio's route data, last checked on January 14, 2026. Prices change often and depend on your travel date. We may earn a commission if you book through our links, at no extra cost to you.
Good to know
- Over land, the quickest option is the train, at about 19h 5m.
- By train the journey takes about 19h 5m, with fares from €131; by bus it takes about 20h 10m, with fares from €64.
- Some connections include a change of train or bus. Omio shows the exact timetable and any changes before you book.
- The flight time covers the flight itself. Allow extra time to reach the airports and pass security, which can make ground transport just as fast on shorter routes.
Where to stay in Prague
Hotels close to the centre of Prague, from budget to luxury. Prices are typical nightly rates at our last check.
Budget
Mid-range
Upscale
LuxuryHotel prices come from Traveloka, last checked on February 4, 2026, and change with your dates. We may earn a commission if you book through our links, at no extra cost to you.
Ready to explore Prague?
About Prague
Prague enchants with its fairy-tale architecture, cobblestone streets, and rich bohemian culture. The City of a Hundred Spires offers stunning Gothic and Baroque landmarks, legendary beer culture, and a magical atmosphere at every turn.
Keep exploring
Return journey
More routes from Rome
More routes to Prague
Frequently asked questions
Quick answers based on current route data.
How long does it take to get from Rome to Prague?+
The quickest option is usually by plane, which takes about 1h 40m.
What is the cheapest way to get from Rome to Prague?+
The cheapest fares are usually by flight, from around €31. Prices depend on the date and how early you book.
Is there a train from Rome to Prague?+
Yes. Omio lists train connections from Rome to Prague, with a typical journey time of about 19h 5m. Some connections may include a change.
Is there a bus from Rome to Prague?+
Yes. Buses run from Rome to Prague, with a typical journey time of about 20h 10m and fares from around €64.
